Parry-Romberg Syndrome and Temporal Lobe Refractory Epilepsy: Case Report.

The Parry-Romberg syndrome (PRS), also known as hemifacial atrophy, is a rare neurocutaneous disease with the prevalence of 1/700,000 cases. It is more common in women than men, with an early onset of disease usually within the first two decades of life. Even though the etiology of PRS is unknown, it is thought to be a multifactorial disease that involves hereditary, posttraumatic, autoimmune, infectious, and neoplastic factors. There are a variety of systemic manifestations described in PRS including neurological conditions that range from intractable headache to refractory epilepsy. The manifestations must be identified in a timely manner to ensure an early therapeutic intervention, considering that an appropriate approach during the initial phase might halt the disease progression and markedly improve the quality of life in these patients. This article is aimed to describe the case of a 23 years old female with left hemifacial atrophy and dermatologic, dental, and neurologic compromise, associated with refractory temporal lobe epilepsy evidenced in neuroimaging and electrodiagnostic testings.

Mega apófisis transversa (Síndrome de Bertolotti) y defecto parcial de fusión posterior sacra como signos con valor identificativo en antropología forense / Anomalous enlargement of the transverse process (Bertolotti's Syndrome) and sacral fusion defect as identification signs in forensic anthropology

Cuando se localizan restos esqueletizados el médico forense debe determinar en primer lugar si éstos son o no humanos. En caso afirmativo, diagnosticar el sexo, ancestro geográfico, edad, altura y si existe alguna patología que permita la identificación. Presentamos un caso con interesantes variaciones óseas: mega apófisis transversa lumbar y un defecto parcial de fusión sacra (AU)

When skeletalized remains are discovered the forensic anthropologist needs to establish first if the bones are human. If so, the sex, race, age, stature, and any pathology must be established in order to make an identification of the remains, determine manner and cause of death. We are presenting a case with interesting bone variations: anomalous enlargement of the transverse process (Bertolotti's syndrome) and partial sacral fusion defect (AU)

Hallazgo incidental de hiperostosis frontal interna o síndrome de Morgagni asociado a meningiomas / Incidental finding of frontal internal hyperostosis or Morgagni syndrome associated with meningiomas

La hiperostosis frontal interna consiste en un engrosamiento de la tabla interna del hueso frontal. Normalmente se encuentra en mujeres post menopáusicas. Presentamos un caso de hallazgo autópsico incidental de hiperostosis frontal interna o síndrome de Morgagni asociado a meningiomas en una mujer postmenopáusica (AU)

Hyperostosis frontalis interna is the accretion of bone on the inner table of the frontal bone. It is commonly found in post-menopausic women. We present an incidental finding of frontal internal hyperostosis or Morgagni syndrome associated with meningiomas in a post-menopausic woman (AU)

Hemoperitoneo secundario a rotura de carcinoma hepatocelular: Hallazgos de autopsia / Hemoperitoenum due to hepatocellular carcinoma. Autopsy findings

El hemoperitoneo secundario a la rotura de un carcinoma hepatocelular (CH) es una complicación poco frecuente en nuestro medio, siendo más infrecuente su hallazgo como causa de muerte en individuos no diagnosticados de CH. Presentamos el caso de una mujer de 87 años con antecedentes patológicos de hepatitis C crónica e hipertensión arterial y sin constancia de traumatismo abdominal previo, que debutó con un cuadro inespecífico de malestar general, náuseas y vómitos de varias horas de evolución, motivo por el cual se le prescribió y administró domiciliariamente metoclopramida. Falleció a las pocas horas de la atención médica, motivo por el cual se practicó la autopsia judicial. Durante la misma se evidenció un hemoperitoneo de 3.000 cc secundario a una rotura intratumoral sobre un hígado cirrótico (AU)

Hemoperitoneum secondary to rupture of hepatocellular carcinoma (CH) is a rare complication in our environment. His find, still more, is uncommon cause of death in individuals not diagnosed of CH. We report the case of a woman of 87 years-old with clinical history of chronic hepatitis C, hypertension, and abdominal trauma without evidence of prior, which debuted with a nonspecific malaise, nausea and vomiting several hours of evolution, why was prescribed and administered metoclopramide home. She died a few hours after care, which is why judicial autopsy was performed. The autopsy was shown a 3000 cc hemoperitoneum secondary to rupture intratumoral in a cirrhotic liver (AU)

Perivascular structures in corrosion casts of the human central nervous system: a confocal laser and scanning electron microscope study.

Scanning electron microscopy (SEM) of microvascular corrosion casts revealed perivascular structures that resembled smooth muscle and pericyte cells. Although these structures have been studied in widely different experimental contexts, their origin, function, and distribution pattern in different tissues are not understood. Microvascular corrosion casts from 15 fresh human brains and 20 lumbar spinal cords were studied by SEM. In five cerebral hemispheres a fluorescent resin was injected in order to study the vascular bed by confocal laser scanning microscopy (CLSM). Microvascular casts showed two perivascular structures on their surfaces: plastic strips, which formed a muff around arteriolar vessels, and pericyte-like structures that were present around the capillary network. Their morphological characteristics and distribution were similar to those of smooth muscle cells and pericytes, respectively. The SEM study showed that these structures were not tightly joined to the cast surface, but were connected to the vascular cast by narrow plastic connections. The CLSM showed that the resin invaded the subendothelial space, thus giving rise to these structures. Perivascular structures associated with arteriolar and capillary vessels appear to represent smooth muscle cells and pericytes. They are formed by the passage of the resin to the subendothelial space, probably through weak endothelial cell junctions. The effusion of resin into the subendothelial space may represent evidence for the structural basis of myocyte and pericyte cell control. Chemical communication by substances released locally or transported to these cells through these junctions may regulate their functions, allowing them to regulate blood flow.